Be certain to complete the prescription unless specifically directed by your veterinarian. The duration of administration depends on the condition being treated, response to the medication and the development of any adverse effects.Extra-label use of drugs in treating animals is allowable only by licensed veterinarians within the context of a valid veterinarian-client-patient relationship, and does not include drug use in treating animals by the layman (except under the supervision of a licensed veterinarian).Federal law restricts this drug to use by or on the order of a licensed veterinarian.Dosage and Administration Silver Sulfadiazine The American Journal of Veterinary research reports that it may be a therapeutic option in the treatment of equine keratomycosis. Ongoing research also shows that silver sulfadiazine may be an effective treatment against common corneal fungal infections in horses. It is also helpful on other shallow, large area wounds such as abrasions. It prevents the growth of a wide array of bacteria, as well as yeast, on damaged skin. Silver sulfadiazine is used primarily as a topical burn cream on second and third degree burns in horses. Silver sulfadiazine is typically delivered in a 1% solution suspended in a water-soluble base. It acts on the cell membrane and cell wall. It is effective against many gram-positive and gram-negative organisms. Very rare (less than 0.Silver sulfadiazine is a broad-spectrum, synthetic antibacterial agent with a chemical structure that includes sulfur and nitrogen atoms. Hematologicįrequency not reported: Neutrophil count decreased, white blood cell depression, agranulocytosis, aplastic anemia, thrombocytopenia, hemolytic anemia DermatologicĬommon (1% to 10%): Pruritus, application site rash, eczema, contact dermatitisįrequency not reported: Skin necrosis, erythema multiforme, skin discoloration, burning sensation, Stevens-Johnson syndrome, toxic epidermal necrolysis, exfoliative dermatitis Renal GeneralĪbsorption varies depending upon the percent of body surface area being treated and extent of tissue damage it is possible any adverse reaction associated with sulfonamides may occur. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.Ĭheck with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Incidence not knownĪpplies to silver sulfadiazine topical: compounding powder, topical cream. These side effects may go away during treatment as your body adjusts to the medicine. Some side effects of silver sulfadiazine topical may occur that usually do not need medical attention. sores, ulcers, or white spots in the mouth or on the lips.red skin lesions, often with a purple center.increased sensitivity of the skin to sunlight, especially in patients with burns on large areas.blistering, peeling, or loosening of the skin.Although not all of these side effects may occur, if they do occur they may need medical attention.Ĭheck with your doctor as soon as possible if any of the following side effects occur while taking silver sulfadiazine topical: Incidence not known Serious side effects of SilvadeneĪlong with its needed effects, silver sulfadiazine topical (the active ingredient contained in Silvadene) may cause some unwanted effects. Some dosage forms listed on this page may not apply to the brand name Silvadene.Īpplies to silver sulfadiazine topical: topical cream. Note: This document contains side effect information about silver sulfadiazine topical. Generic name: silver sulfadiazine topical
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